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Impiego pratico delle cellule staminali nel trattamento dell’artrosi nel cane

Bibliografia

 

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2. Arzi B, Taechangam N, Lommer MJ et coll. Stem cell therapy prior to full-mouth tooth extraction lacks substantial clinical efficacy in cats affected by chronic gingivostomatitis. J. Feline Med. Surg. 2021;23(6):604-608.

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6. Cabon Q, Febre M, Gomez N et coll. Long-term safety and efficacy of single or repeated intra-articular injection of allogeneic neonatal mesenchymal stromal cells for managing pain and lameness in moderate to severe canine osteoarthritis without anti-inflammatory pharmacological support: pilot clinical study. Front. Vet. Sci. 2019;6:10.

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10. Ivanovska A, Wang M, Arshaghi TE et coll. Manufacturing mesenchymal stromal cells for the treatment of osteoarthritis in canine patients: challenges and recommendations. Front. Vet. Sci. 2022;9:897150.

11. Kalairaj MS, Pradhan R, Saleem W et coll. Intra-articular injectable biomaterials therapeutic delivery for cartilage repair and regeneration. Adv. Healthc. Mater. 2024;13(17):e2303794.

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13. Kim SE, Elam L, Johnson V et coll. Intra-articular injections of allogeneic mesenchymal stromal cells vs. high molecular weight hyaluronic acid in dogs with osteoarthritis: exploratory data from a double-blind, randomized, prospective clinical trial. Front. Vet. Sci. 2022;9:890704.

14. Kim SE, Pozzi A, Yeh JC et coll. Intra-articular umbilical cord derived mesenchymal stem cell therapy for chronic elbow osteoarthritis in dogs: a doubleblinded, placebo-controlled clinical trial. Front. Vet. Sci. 2019;9:474.

15. Kriston-Pál E, Czibula A, Gyuris Z et coll. Characterization and therapeutic application of canine adipose mesenchymal stem cells to treat elbow osteoarthritis. Can. J. Vet. Res. 2017;81(1):73-78.

16. Kriston-Pál E, Haracska L, Cooper P et coll. A regenerative approach to canine osteoarthritis using allogeneic, adipose-derived mesenchymal stem cells. Safety results of a long-term follow-up. Front. Vet. Sci. 2020;7:510.

17. Kulus M, Kulus J, Jankowski M et coll. The use of mesenchymal stem cells in veterinary medicine. Med. J. Cell Biol. 2018;6:101-107.

18. Mielke B, Comerford E, English K et coll. Spontaneous septic arthritis of canine elbows: twenty-one cases. Vet. Comp. Orthop. Traumatol. 2018;31(6):488-493.

19. Migliorini F, Rath B, Colarossi G et coll. Improved outcomes after mesenchymal stem cells injections for knee osteoarthritis: results at 12-months follow-up, a systematic review of the literatur. Arch. Orthop. Trauma Surg. 2020;140(7):853-868.

20. Miller AV, Carney PC, Markmann A et coll. Retrospective analysis describes safety of therapeutic joint injections in dogs. J. Am. Vet. Med. Assoc. 2023;261(3):397-402.

21. Olsen A, Johnson V, Webb T et coll. Evaluation of intravenously delivered allogeneic mesenchymal stem cells for treatment of elbow osteoarthritis in dogs: a pilot study. Vet. Comp. Orthop. Traumatol. 2019;32(3):173-181.

22. Pavarotti G, Hivernaud V, Brincin M et coll. Evaluation of a single intra-articular injection of autologous adipose tissue for the treatment of osteoarthritis: a prospective clinical study in dogs. Vet. Comp. Orthop. Traumatol. 2020;33(4):258-266.

23. Pers YM, Rackwitz L, Ferreira R et coll. Adipose mesenchymal stromal cell-based therapy for severe osteoarthritis of the knee: a phase I dose-escalation trial. Stem Cells Transl. Med. 2016;5(7):847-856.

24. Przadka P, Buczak K, Frejlich E et coll. The role of mesenchymal stem cells (MSCs) in veterinary medicine and their use in musculoskeletal disorders. Biomolecules. 2021;11(8):1141.

25. Punzón E, Salgüero R, Totusaus X et coll. Equine umbilical cord mesenchymal stem cells demonstrate safety and efficacy in the treatment of canine osteoarthritis: a randomized placebo-controlled trial. J. Am. Vet. Med. Assoc. 2022;260(15):1947-1955.

26. Punzon E, Garcia-Castillo M, Rico MA et coll. Local, systemic and immunologic safety comparison between xenogeneic equine umbilical cord mesenchymal stem cells, allogeneic canine adipose mesenchymal stem cells and placebo: a randomized controlled trial. Front. Vet. Sci. 2023;10:1098029.

27. Sanghani-Kerai A, Black C, Cheng SO et coll. Clinical outcomes following intraarticular injection of autologous adipose-derived mesenchymal stem cells for the treatment of osteoarthritis in dogs characterized by weight-bearing asymmetry. Bone Joint Res. 2021;10(10):650-658.

28. Shah K, Drury T, Roic I et coll. Outcome of allogeneic adult stem cell therapy in dogs suffering from osteoarthritis and other joint defects. Stem Cells Int. 2018;2018:7309201.

29. Soltero-Rivera M, Hart S, Blandino A et coll. Mesenchymal stromal cell therapy for feline chronic gingivostomatitis: long term experience. Front. Vet. Sci. 2023;10:1171922.

30. Taroni M, Cabon Q, Fèbre M et coll. Evaluation of the effect of a single intraarticular injection of allogeneic neonatal mesenchymal stromal cells compared to oral non-steroidal anti-inflammatory treatment on the postoperative musculoskeletal status and gait of dogs over a 6-month period after tibial plateau leveling osteotomy: a pilot study. Front. Vet. Sci. 2017;4:83.

31. Voga M, Adamic N, Vengust M et coll. Stem cells in veterinary medicine-current state and treatment options. Front. Vet. Sci. 2020;7:278.

 

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29/05/2025

Eradicazione di M. hyopneumoniae nel suino: gli strumenti ci sono

I metodi storicamente impiegati per ridurre l’incidenza delle infezioni da M. hyopneumoniae non sembrano attualmente funzionare adeguatamente. I programmi di controllo per questo microrganismo si dividono in due macrocategorie: i programmi che prevedono l’eradicazione dell’agente patogeno e quelli che non la prevedono; a quest’ultima categoria appartengono le strategie che si basano su tre concetti: gestione, prevenzione e trattamento.

 
 

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