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1. Babatunde SM, Ramanoon SZ, Shaik Mossadeq WM, Mansor R, Syed Hussain SS. Dairy farmers' perceptions of and actions in relation to lameness management. Animals (Basel). 2019 May 23;9(5):270. doi: 10.3390/ani9050270. PMID: 31126064; PMCID: PMC6562916.

2. Benedet A, Manuelian CL, Zidi A, Penasa M, De Marchi M. Invited review: β-hydroxybutyrate concentration in blood and milk and its associations with cow performance. Animal. 2019 Aug;13(8):1676-1689. doi: 10.1017/S175173111900034X. Epub 2019 Mar 11. PMID: 30854998.

3. Capel MB, Bach KD, Mann S, McArt JAA. A randomized controlled trial to evaluate propylene glycol alone or in combination with dextrose as a treatment for hyperketonemia in dairy cows. J Dairy Sci. 2021 Feb;104(2):2185-2194. doi:10.3168/jds.2020-19111. Epub 2020 Dec 11. PMID: 33309356.

4. Dubuc J, Buczinski S. Short communication: Cow- and herd-level prevalence of hypoglycemia in hyperketonemic postpartum dairy cows. J Dairy Sci. 2018 Apr;101(4):3374-3379. doi: 10.3168/jds.2017-13773. Epub 2018 Feb 7. PMID: 29428744.

5. Duffield TF, Lissemore KD, McBride BW, Leslie KE. Impact of hyperketonemia in early lactation dairy cows on health and production. J Dairy Sci. 2009 Feb;92(2):571-80. doi: 10.3168/jds.2008-1507. PMID: 19164667.

6. Gohary K, Overton MW, Von Massow M, LeBlanc SJ, Lissemore KD, Duffield TF. The cost of a case of subclinical ketosis in Canadian dairy herds. Can Vet J. 2016 Jul;57(7):728-32. PMID: 27429460; PMCID: PMC4904808.

7. Gordon JL, Leblanc SJ, Duffield TF. Ketosis treatment in lactating dairy cattle. Vet Clin North Am Food Anim Pract. 2013 Jul;29(2):433-45. doi: 10.1016/j.cvfa.2013.03.001. Epub 2013 May 4. PMID: 23809899.

8. Gordon JL, Duffield TF, Herdt TH, Kelton DF, Neuder L, LeBlanc SJ. Effects of a combination butaphosphan and cyanocobalamin product and insulin on ketosis resolution and milk production. J Dairy Sci. 2017 Apr;100(4):2954-2966. doi:10.3168/jds.2016-11925. Epub 2017 Feb 16. PMID: 28215889; a.

9. Gordon JL, LeBlanc SJ, Kelton DF, Herdt TH, Neuder L, Duffield TF. Randomized clinical field trial on the effects of butaphosphan-cyanocobalamin and propylene glycol on ketosis resolution and milk production. J Dairy Sci.2017 May;100(5):3912-3921. doi: 10.3168/jds.2016-11926. Epub 2017 Mar 2. PMID:28259407; b.

10. Guliński P. Ketone bodies - causes and effects of their increased presence in cows' body fluids: A review. Vet World. 2021 Jun;14(6):1492-1503. doi: 10.14202/vetworld.2021.1492-1503. Epub 2021 Jun 11. PMID: 34316197; PMCID: PMC8304442.

11. Hubner AM, Canisso IF, Peixoto PM, Coelho WM Jr, Ribeiro L, Aldridge BM, Lima FS. A randomized controlled trial examining the effects of treatment with propylene glycol and injectable cyanocobalamin on naturally occurring disease, milk production, and reproductive outcomes of dairy cows diagnosed with concurrent hyperketonemia and hypoglycemia. J Dairy Sci. 2022 Sep13:S0022-0302(22)00520-3. doi: 10.3168/jds.2021-21328. Epub ahead of print.PMID: 36114052.

12. Loiklung C, Sukon P, Thamrongyoswittayakul C. Global prevalence of subclinical ketosis in dairy cows: A systematic review and meta-analysis. Res Vet Sci. 2022 May;144:66-76. doi: 10.1016/j.rvsc.2022.01.003. Epub 2022 Jan 17. PMID: 35077992.

13. Faruk M.S., Park B., Ha S., Lee S., Mamuad L., Cho Y. (2020): Comparative study on different field tests of ketosis using blood, milk, and urine in dairy cattle. Veterinarni Medicina, 65: 199-206. doi:10.17221/69/2019-VETMED

14. Macrae AI, Burrough E, Forrest J, Corbishley A, Russell G, Shaw DJ. Prevalence of excessive negative energy balance in commercial United Kingdom dairy herds. Vet J. 2019 Jun;248:51-57. doi: 10.1016/j.tvjl.2019.04.001. Epub 2019 Apr 5. PMID: 31113563.

15. Mann S, Yepes FAL, Behling-Kelly E, McArt JAA. The effect of different treatments for early-lactation hyperketonemia on blood β-hydroxybutyrate, plasma non esterified fatty acids, glucose, insulin, and glucagon in dairy cattle. JDairy Sci. 2017 Aug;100(8):6470-6482. doi: 10.3168/jds.2016-12532. Epub 2017 May24. PMID: 28551184.

16. McArt JA, Nydam DV, Oetzel GR, Overton TR, Ospina PA. Elevated non-esterified fatty acids and β-hydroxybutyrate and their association with transition dairy cow performance. Vet J. 2013 Dec;198(3):560-70. doi: 10.1016/j.tvjl.2013.08.011. Epub 2013 Aug 16. PMID: 24054909.

17. Moore SM, King MTM, Carpenter AJ, DeVries TJ. Behavior, health, and productivity of early-lactation dairy cows supplemented with molasses in automated milking systems. J Dairy Sci. 2020 Nov;103(11):10506-10518. doi: 10.3168/jds.2020-18649. Epub 2020 Sep 10. PMID: 32921474.

18. Mostert PF, Bokkers EAM, van Middelaar CE, Hogeveen H, de Boer IJM. Estimating the economic impact of subclinical ketosis in dairy cattle using a dynamic stochastic simulation model. Animal. 2018 Jan;12(1):145-154. doi: 10.1017/S1751731117001306. Epub 2017 Jun 22. PMID: 28637532.

19. Nielsen NI, Ingvartsen KL. Propylene glycol for dairy cows: A review of the metabolism of propylene glycol and its effects on physiological parameters, feed intake, milk production and risk of ketosis. Animal Feed Science and Technology. Volume 115, 2004 Aug;115(3–4):191-213. doi: 10.1016/j.anifeedsci.2004.03.008.

20. Raboisson D, Mounié M, Maigné E. Diseases, reproductive performance, and changes in milk production associated with subclinical ketosis in dairy cows: a meta-analysis and review. J Dairy Sci. 2014 Dec;97(12):7547-63. doi: 10.3168/jds.2014-8237. Epub 2014 Oct 11. PMID: 25306269.

21. Raboisson D, Mounié M, Khenifar E, Maigné E. The economic impact of subclinical ketosis at the farm level: Tackling the challenge of over-estimation due to multiple interactions. Prev Vet Med. 2015 Dec 1;122(4):417-25. doi: 10.1016/j.prevetmed.2015.07.010. Epub 2015 Jul 28. PMID: 26276398.

22. Randall LV, Green MJ, Chagunda MG, Mason C, Archer SC, Green LE, Huxley JN. Low body condition predisposes cattle to lameness: An 8-year study of one dairy herd. J Dairy Sci. 2015 Jun;98(6):3766-77. doi: 10.3168/jds.2014-8863. Epub 2015 Mar 28. PMID: 25828666.

23. Rutherford AJ, Oikonomou G, Smith RF. The effect of subclinical ketosis on activity at estrus and reproductive performance in dairy cattle. J Dairy Sci. 2016 Jun;99(6):4808-4815. doi: 10.3168/jds.2015-10154. Epub 2016 Mar 16. PMID: 26995121.

24. Suthar VS, Canelas-Raposo J, Deniz A, Heuwieser W. Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. J Dairy Sci. 2013 May;96(5):2925-38. doi: 10.3168/jds.2012-6035. Epub 2013 Mar 15. PMID: 23497997.

25. Tatone EH, Duffield TF, Capel MB, DeVries TJ, LeBlanc SJ, Gordon JL. A randomized controlled trial of dexamethasone as an adjunctive therapy to propylene glycol for treatment of hyperketonemia in postpartum dairy cattle. JDairy Sci. 2016 Nov;99(11):8991-9000. doi: 10.3168/jds.2016-11358. Epub 2016 Sep13. PMID: 27638258.

26. Tatone EH, Duffield TF, LeBlanc SJ, DeVries TJ, Gordon JL. Investigating the within-herd prevalence and risk factors for ketosis in dairy cattle in Ontario as diagnosed by the test-day concentration of β-hydroxybutyrate in milk. J Dairy Sci. 2017 Feb;100(2):1308-1318. doi: 10.3168/jds.2016-11453. Epub 2016 Dec 21. PMID: 28012623.

27. Williamson M, Couto Serrenho R, McBride BW, LeBlanc SJ, DeVries TJ, DuffieldTF. Reducing milking frequency from twice to once daily as an adjunct treatment for ketosis in lactating dairy cows-A randomized controlled trial. J Dairy Sci.2022 Feb;105(2):1402-1417. doi: 10.3168/jds.2021-20551. Epub 2021 Nov 17. PMID:34799108.

28. Wynands EM, Caixeta LS, Cramer G. Using a target trial approach to evaluate the role of hyperketonemia in sole ulcer and white line hoof lesion development. J Dairy Sci. 2022 Jul;105(7):6164-6174. doi: 10.3168/jds.2021-21694. Epub 2022 May 20. PMID: 35599034.


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