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Nei suini la stimolazione della crescita mediante antibiotici risulta correlata a un rimodellamento tessuto-specifico delle caratteristiche degli acidi biliari e del loro sistema di trasduzione del segnale

 

 


www.nature.com/scientificreports/

  1. Kim, H. B. et al. Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. Proc. Natl. Acad. Sci. USA 109, 15485–15490 (2012).

  2. Looft, T. et al. In-feed antibiotic effects on the swine intestinal microbiome. Proc. Natl. Acad. Sci. USA 109, 1691–1696 (2012).

  3. Saltiel, A. R. & Kahn, C. R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414, 799–806 (2001).

  4. Joyce, S. A. & Gahan, C. G. M. Bile acid modifications at the microbe-host interface: potential for nutraceutical and pharmaceutical

    interventions in host health. Annu. Rev. Food Sci. Technol. 7, 313–333 (2016).

  5. Ridlon, J. M., Kang, D.-J. & Hylemon, P. B. Bile salt biotransformations by human intestinal bacteria. J. Lipid Res. 47, 241–259 (2006).

  6. Lundell, K. & Wikvall, K. Species-specific and age-dependent bile acid composition: aspects on CYP8B and CYP4A subfamilies in

    bile acid biosynthesis. Curr. Drug Metab. 9, 323–331 (2008).

  7. Keely, S. J. & Walters, J. R. F. The farnesoid Xreceptor: good for BAD. Cell Mol. Gastroenterol. Hepatol. 2, 725–732 (2016).

  8. Bunnett, N. W. Neuro-humoral signalling by bile acids and the TGR5 receptor in the gastrointestinal tract. J. Physiol. 592, 2943–2950

    (2014).

  9. Pathak, P. et al. Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic

    metabolism. J. Biol. Chem. 292, 11055–11069 (2017).

  10. Burrin, D., Stoll, B. & Moore, D. Digestive physiology of the pig: intestinal bile acid sensing is linked to key endocrine and metabolic

    signaling pathways. J. Anim. Sci. 91, 1991–2000 (2013).

  11. Jain, A. K., Stoll, B., Burrin, D. G., Holst, J. J. & Moore, D. D. Enteral bile acid treatment improves parenteral nutrition-related liver

    disease and intestinal mucosal atrophy in neonatal pigs. Am. J. Physiol. Gastrointest. Liver Physiol. 302, G218–G224 (2012).

  12. de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, J. J. & Ipharraguerre, I. R. Bile acid mediated effects on gut integrity and

    performance of early-weaned piglets. BMC Vet. Res. 11, 111 (2015).

  13. Watanabe, M. et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J. Clin. Invest. 113,

    1408–1418 (2004).

  14. Jones, S. A. Physiology of FGF15/19. Endocrine FGFs and Klothos, ed. Kuro-o, M. (Springer US, New York, NY), 171–182 (2012).

  15. Potthoff, M. J., Kliewer, S. A. & Mangelsdorf, D. J. Endocrine fibroblast growth factors 15/19 and 21: from feast to famine. Genes Dev.

    26, 312–324 (2012).

  16. Gavaldà-Navarro, A., Pastor, J. J., Mereu, A., Villarroya, F. & Ipharraguerre, I. R. Developmental regulation of the FGF19 system in

    domestic pigs. Am. J. Physiol. Gastrointest. Liver. Physiol. 314, G647–G654 (2018).

  17. Bhatnagar, S., Damron, H. A. & Hillgartner, F. B. Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis.

    J. Biol. Chem. 284, 10023–10033 (2009).

  18. Lan, T. et al. FGF19, FGF21, and an FGFR1/β-Klotho-activating antibody act on the nervous system to regulate body weight and

    glycemia. Cell Metab. 26, 709–718 (2017).

  19. Iseri, V. J. & Klasing, K. C. Changes in the amount of lysine in protective proteins and immune cells after a systemic response to dead

    Escherichia coli: implications for the nutritional costs of immunity. Integr. Comp. Biol. 54, 922–930 (2014).

  20. Hotamisligil, G. S. Foundations of immunometabolism and implications for metabolic health and disease. Immunity 47, 406–420

    (2017).

  21. Caporaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nat. Methods 7, 335–336 (2010).

 

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Black Friday 2019 PVI


Dal web internazionale
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I fabbisogni nutritivi per la fertilità maschile e femminile

L’alimentazione ha riflessi su molteplici aspetti: fertilità, produzione di latte, immunità, produzione di lana, adattamento ai diversi stress ambientali.

 
 

Formazione a distanza abbinata a SUMMA

 

 

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